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Home Machine Learning

Pharmacy Placement in City Spain

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May 8, 2025
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1.- AND BACKGROUND.

1.1.- INTRODUCTION

This case examine demonstrates the usage of Geospatial applied sciences to deal with a enterprise problem within the growth of the pharmacy community within the Group of Madrid, Spain. This evaluation is predicated on a venture that features authorized, city planning, engineering, administrative legislation and enterprise concerns, however these facets are outdoors the scope of this evaluation. Right here we focus completely on the appliance of superior geospatial applied sciences, similar to OSMnx and NetworkX, to beat the geospatial challenges concerned within the deployment of the pharmacy community, particularly the right way to discover gaps within the city pharmacy community the place it’s attainable to put in a brand new pharmacy whereas respecting the authorized restrictions on the minimal distance between pharmacies.

1.2.- BACKGROUND

The pharmaceutical sector in Spain is regulated by the federal government with the intention of making certain the provision and allotting of medicines below applicable high quality and worth situations. Inside this sector, distribution is affected by quite a few limitations similar to: the possession, location and technical-economic situations of pharmacies via state legal guidelines [1] and quite a few laws of the Autonomous Communities. This publication will take care of the constraints relating to location within the Autonomous Group of Madrid.

In relation to funding within the community of pharmacies in Spain normally, and within the Autonomous Group of Madrid specifically, the fascinating downside of discovering appropriate places for organising a pharmacy arises. Though this seek for places could be in new city areas below growth, essentially the most fascinating is consolidated city land. It’s because the funding maturity interval is shorter, as there’s already a inhabitants residing within the space, and the inhabitants density is often increased than that deliberate for growth areas. Nevertheless, the issue is that in these consolidated city areas there are already pharmacies in operation and the minimal distances between them have to be revered by legislation.

The Spanish authorized framework for the pharmaceutical sector establishes a minimal distance limitation of 250 m between pharmacies with the intention to find a pharmacy workplace [2], [3]. This distance needs to be measured by following a route in line with the next concerns:

  • It needs to be a route much like that which a pedestrian would observe.
  • It ought to join the centres of the fronts of pharmacies, not the entrances to pharmacies.

As well as, it have to be ensured that the gap to public well being services is greater than 150 m measured alongside a pedestrian route.

Some points are highlighted under:

  • Pharmacies established prior to those legal guidelines don’t observe these guidelines, with the outcome that some pharmacies are positioned at a distance of lower than 250m. Regardless of this, there are nonetheless city openings for the placement of latest pharmacies in areas of curiosity from the perspective of the pharmaceutical enterprise.
  • The existence of those city openings will not be sufficient and requires extra fieldwork to analyse the existence of obtainable properties to deal with the pharmacy in these areas and to review the chance provided by city planning to really set up a pharmacy in these areas. That is due to this fact a primary step within the funding course of.

The effectiveness of open-source instruments similar to OSMnx [4] and Networkx [5] in addressing advanced issues associated to city material evaluation, city transport and mobility has been demonstrated in quite a few publications [6]–[8]. The intention of this publication is to current a technique based mostly on OSMnx and NerworkX to disclose potential openings (alternatives) within the city material for the placement of pharmacies bearing in mind the authorized restrictions.

NetworkX is a Python library designed for the appliance of graph principle [9] to analyse advanced networks of relationships. It operates via an advanced framework of objects, the place the fundamental components are nodes, that are interconnected by edges, representing relationships between nodes. This device is extensively employed within the examine, evaluation, and determination of real-world issues, together with however not restricted to geospatial transportation networks, city geospatial networks, and social networks. OSMnx is a specialised open-source python library that makes use of OpenStreetMap geospatial information to vectorize the road networks of cities globally as NetworkX graphs, facilitating their evaluation via Python code. This strategy is exemplified in [10], the place numerous city areas worldwide are systematically analyzed.

Given the quite a few variables and alternate options to contemplate when using these instruments to deal with geospatial challenges, a broad collection of publications on the topic has been reviewed. Because of the progressive and quickly evolving nature of those instruments, a few of these sources are completely out there via on-line boards, similar to https://stackoverflow.com/, or in web-native scientific journals. A key problem that has prompted appreciable debate in these sources is the tactic for connecting factors of curiosity (POIs) to the town graphs of OSMnx, as mentioned in [11] – [12], to allow computations over these graphs to resolve issues associated to the POIs. For the particular case addressed on this paper—the localization of pharmacy workplaces (POIs) in compliance with authorized distance necessities—a brand new methodology has been developed to greatest swimsuit the case, drawing on the related literature and on-line assets consulted. This system will probably be offered within the methodology part and is anticipated to be relevant to related circumstances.

2.- METHOD

After gathering the required information: UTM coordinates of the pharmacies and the suitable OSMnx graph of the town of Madrid, a primary part of this system consists of projecting the UTM coordinates of the pharmacies onto the OSMnx grid of Madrid as nodes. To do that, first, the sides of the OSMnx graph closest to every pharmacy will probably be recognized within the “Knowledge Placement on the Grid” part of this system. That is finished by importing the OSMnx graph with out simplifying it. This manner, all of the curved traces of the Madrid city graph could be approximated by a number of traces of decreased measurement, appropriate for subsequent vector calculation. Moreover, on this case it’s essential to venture the UTM coordinates of the pharmacy workplaces, that are often positioned inside their institutions, onto the OSMnx graph. That is finished within the ‘Vector calculation’ part of the methodology. On this manner, the placement of the midpoints of their façades on the general public street is approximated.

Thirdly, as soon as the UTM coordinates of the pharmacies have been projected as nodes of the OSMnx graph of the town of Madrid, within the subsequent ‘Grid Overlay’ part, the areas of the community which might be lower than 250 m from every of the pharmacy-nodes are calculated. For this objective, we don’t think about the Euclidean distance however the topological distance, in line with the walkable city graph. Thus, n networks are obtained, one per pharmacy. Then, all of them are superimposed. Lastly, the results of this superposition is subtracted from the OSMnx graph of Madrid. The results of this subtraction is a brand new community with the sides which might be greater than 250 m away from any pharmacy. Lastly, this result’s visualised as the ultimate answer, since these edges represent the axes on which a pharmacy workplace could be housed from the topological perspective.

For example this publication and take a look at the methodology, an city space with a really sophisticated city material has been chosen, centred on the Madrid district of Tetuán, the place pharmacies are additionally very shut to one another, as a few of them have been put in earlier than the inclusion of the gap limitation within the authorized framework.

To simplify the preliminary exposition of the methodology, the minimal authorized distance situation of 150 m to well being centres has been disbursed with, contemplating solely the minimal distance between pharmacies as a limiting issue. As soon as the methodology has been defined in its entirety, it will likely be seen how this situation is definitely launched within the ‘dialogue’ part.

Every part of the methodology is defined intimately under.

2.1.- Knowledge assortment

The Group of Madrid has publicly out there information on its pharmacies and well being centres: addresses, codes, geographic coordinates, pharmacist in cost, and so on. These information can be found on the net [13]. The csv recordsdata used on this publication have been extracted from it [14]. For the reason that factors to be thought of for the calculation of distances needs to be the midpoints of the facades, and never the accesses to the pharmacies, it’s a higher approximation to make use of the UTM coordinates of the centre of the pharmacy institutions and venture them onto the OSMnx graph, as a substitute of geocoding the addresses of the pharmacies. On this manner, the centre of the pharmacy institutions could be higher approximated. That is significantly vital within the case of pharmacy premises with lengthy facades or nook facades, the place the geolocation of the premises is assigned to the doorway and to not the center level of the facade, which is the purpose referred to within the distance measurement regulation.

As for the OSMnx community to be thought of, it will likely be of kind ‘stroll’ (network_type=’stroll’) [15], which incorporates all public pedestrian routes in Madrid. Since a part of the methodology makes use of vector calculations, the default simplification of the OSMnx community is discarded (therefore, simplify= ’False’) with the intention to receive the totality of the community nodes [16]. Thus, the curved elements of the community could be approximated by straight traces between the ‘nodes’ of the ‘edges’. With respect to this earlier publication, on this case, as well as the centre of the pharmacy institutions must also be projected onto the OSMnx community. As a conclusion of the above dialogue, the Madrid graph will probably be imported as follows in code 1:

Madrid_graph = ox.graph_from_place('Madrid, Spain', network_type='stroll', 
                             simplify= False )

Code 1. Python 3.11.5.

2.2.- Knowledge placement on the grid

As defined above, step one is to determine the sides of the detailed model of the OSMnx graph of Madrid which might be closest to every pharmacy. That is finished via the OSMnx distances module, saving the info of every nearest edge within the corresponding row of the pharmacies DataFrame, in addition to the gap, as a verify, code 2.

for index, row in farmacias.iterrows():
    edge = ox.distance.nearest_edges(Madrid_graph, row['lon'], 
                                     row['lat'], return_dist=True)
    node = ox.distance.nearest_nodes(Madrid_graph, row['lon'], 
                                     row['lat'], return_dist=True)
    farmacias.loc[index,'edge_1'] = str(edge[0][0])
    farmacias.loc[index,'edge_2'] = str(edge[0][1])
    farmacias.loc[index,'edge_n'] = str(edge[0][2])
    farmacias.loc[index,'edge_d'] = edge[1]
    farmacias.loc[index,'node'] = str(node[0])
    farmacias.loc[index,'node_d'] = node[1]

Code 2. Python 3.11.5. ‘lon’ and ‘lat’ stand for the geographical coordinates Longitude and Latitude.

Though not needed for the next calculations, the identification of the closest node has additionally been included for data and high quality management functions.

These are proven under in Fig. 1 for the chosen Madrid pilot surroundings.

Fig. 1. Knowledge Placement on the grid. UTM coordinates of the pharmacies, blue factors. Nearest nodes of the graph, crimson factors. Closest edges of the graph, crimson segments. Personal elaboration utilizing OSMnx. Knowledge © OpenStreetMap contributors, out there below the Open Database License

2.3.- Vector calculation

So as to venture the pharmacies on the graph of Madrid, it’s taken under consideration that what’s of curiosity on this case is to determine the midpoint of their façade on the general public methods, i.e. on the graph. As talked about above, usually, the UTM supplied within the Public Administration recordsdata refer to a degree contained in the business institution. Subsequently, it’s essential to venture these factors on the Madrid graph, reworking them into a brand new node of the graph. On this case, it isn’t appropriate to hyperlink pharmacies to the graph via an edge, since solely pedestrian routes on public methods are of curiosity for distance measurement. So, as a substitute, a brand new node needs to be created the place every pharmacy workplace is projected on the graph, on the closest edge decided within the earlier part.

The projection is carried out utilizing the Python library Numpy [17] utilizing the next vector calculation, which offers the coordinates of the brand new P nodes which might be the projection of every pharmacy on the graph, Fig. 2:

Fig. 2. Vector calculation scheme. F, pharmacy UTM level. P, projected pharmacy node. E1 and E2, edge ends. L, is the size of the sting in OSMnx. Personal elaboration.

Within the case that “d” or “L2” is damaging, which might happen because of small variations between the lengths of the sides in OSMnx and the projections made utilizing UTM coordinates, the node the place the pharmacy is projected will probably be one of many excessive nodes defining the sting, relying on which of the 2 portions is damaging. If “d” is damaging, then the pharmacy will probably be projected as “E1”; if “L2” is damaging, then as “E2”.

Thus, a brand new edge is created that connects this new node with the nodes of the closest edge. Subsequently, the beforehand decided nearest edge is deleted, as it’s changed by the one simply created. See code 3.

for index, row in farmacias.iterrows():
    # vector calculation
    F = np.array( [row['localizacion_coordenada_x'], row['localizacion_coordenada_y']])
    E1 = np.array([utm.from_latlon(Madrid_graph.nodes[row['edge_1']]['y'], Madrid_graph.nodes[row['edge_1']]['x'], 30,'N')[0],
                   utm.from_latlon(Madrid_graph.nodes[row['edge_1']]['y'], Madrid_graph.nodes[row['edge_1']]['x'], 30,'N')[1]])
    E2 = np.array([utm.from_latlon(Madrid_graph.nodes[row['edge_2']]['y'], Madrid_graph.nodes[row['edge_2']]['x'], 30,'N')[0],
                   utm.from_latlon(Madrid_graph.nodes[row['edge_2']]['y'], Madrid_graph.nodes[row['edge_2']]['x'], 30,'N')[1]])
    d = np.dot(E2-E1,F-E1)/Madrid_graph.edges[(row['edge_1'],row['edge_2'],row['edge_n'] )]['length']
    d_vect = (E2-E1)*d/Madrid_graph.edges[(row['edge_1'],row['edge_2'],row['edge_n'] )]['length']
    F_coord = E1 + d_vect
    L_calculada = np.sqrt(np.dot(E2-E1,E2-E1))
    F_coord_LL = utm.to_latlon(F_coord[0], F_coord[1], 30, 'N')
    L2 = Madrid_graph.edges[(row['edge_1'],row['edge_2'],row['edge_n'] )]['length'] - d
    # edge and node substitution
    if d<0:  
        nx.relabel_nodes(Madrid_graph, {row['edge_1']: row['farmacia_nro_soe']}, copy= False)
        nx.set_node_attributes(Madrid_graph, { row['farmacia_nro_soe'] :{'shade':'r', 'measurement':10 }}  )                            
    elif L2<0:
        nx.relabel_nodes(Madrid_graph, {row['edge_2']: row['farmacia_nro_soe']}, copy=False)
        nx.set_node_attributes(Madrid_graph, { row['farmacia_nro_soe'] :{'shade':'r', 'measurement':10 }}  )     
    else:
        Madrid_graph.add_edge(row['edge_1'],row['farmacia_nro_soe'],0)
        nx.set_edge_attributes(Madrid_graph, { (row['edge_1'], row['farmacia_nro_soe'], 
                                            0):{'size':d, 'osmid' : row['farmacia_nro_soe'], 'shade':'r', 'measurement':4  }})
        Madrid_graph.add_edge(row['farmacia_nro_soe'],row['edge_2'],0)
        nx.set_edge_attributes(Madrid_graph, { (row['farmacia_nro_soe'], row['edge_2'], 
                                            0):{'size':L2 , 'osmid' : row['farmacia_nro_soe'], 'shade':'r', 'measurement':4 }})
        Madrid_graph.remove_edge(row['edge_1'],row['edge_2'],row['edge_n'] )  
        nx.set_node_attributes(Madrid_graph, 
                               { row['farmacia_nro_soe'] :{'x':F_coord_LL[1], 'y':F_coord_LL[0], 'shade':'r', 'measurement':10 }}  )

Code 3. . Python 3.11.5. ‘farmacia_nro_soe’ stands for pharmacy code. The variables to start with (F, E1, E2, d, and so on) consult with these in Fig. 2. The opposite attributes of nodes and edges (‘shade’, ‘measurement’) are supposed to focus on them within the drawing course of.

The results of this calculation is proven in Fig. 3

Fig. 3. Projected pharmacies as crimson nodes within the Madrid graph. Personal elaboration utilizing OSMnx. Knowledge © OpenStreetMap contributors, out there below the Open Database License

2.4.- Grid overlay.

On this part we’re going to create graphs of 250 m strolling distance with centre at every of the pharmacy nodes in Madrid: nx.mills.ego_graph([...], radius=250, centre=True, distance=’size‘). They’re then composed to kind a bigger one containing all of them: MultiGraph.nx.compose_all(). They’re then subtracted from the bottom Madrid graph initially used: MultiGraph.remove_edges_from(). This graph with the sides and nodes remaining after the subtraction accommodates edges that meet the situation of getting all their factors positioned greater than 250 m from all the opposite pharmacy nodes, due to this fact, prone to home a brand new pharmacy, code 4.

for index, row in farmacias.iterrows():
    Grph = nx.mills.ego_graph(Madrid_graph,row['farmacia_nro_soe'] , 
                                   undirected=True, radius=250, 
                                   heart=True, distance='size')
    superposicion.append(Grph)
S = nx.compose_all(superposicion)
nx.set_edge_attributes(S, 'r', 'shade' )
Madrid_graph.remove_edges_from(checklist(S.edges))    

Code 4. . Python 3.11.5. ‘farmacia_nro_soe’ stands for pharmacy code. 

3.- RESULTS

Fig. 4 reveals the results of making use of the process to the set of pharmacies represented by the inexperienced dots solely in an almond-shaped space of the town of Madrid. All edges containing factors which might be lower than 250 m away from the given pharmacy community have been eliminated, so {that a} hole is noticed inside the illustration. The perimeters which might be nonetheless current inside the hole after the removing are these the place it might be attainable to deal with a brand new pharmacy from a topological perspective. Clearly, within the precise venture it’s essential to verify the city situations of those ‘edges’, in addition to the supply of a business actual property to deal with a pharmacy, see the next part.

Fig. 4. End result: the sides the place it might be attainable to host new pharmacies, given a constellation of current pharmacies as blue dots. The perimeters of the graph positioned outdoors the topological distance of 250 m inside the given constellation of pharmacies, proven as crimson segments, are attainable appropriate places for a pharmacy. Gray background: shadows of buildings. Personal elaboration utilizing OSMnx. Knowledge © OpenStreetMap contributors, out there below the Open Database License

4.- DISCUSSION AND CONCLUSIONS

4.1.-Graph choice

Provided that pharmacy workplaces in Spain can solely be positioned on public pathways and that the 250 m distance limitations between pharmacy workplaces are measured via pedestrian routes, the community kind ‘stroll’ [15], which incorporates all public pedestrian routes in Madrid, has been chosen because the OSMnx Madrid graph, code 5.

Madrid_graph = ox.graph_from_place('Madrid, Spain', network_type='stroll', 
                             simplify= False )

Code 5. Python 3.11.5

In circumstances completely different from the one at hand, during which not solely public roads are helpful for the work, but additionally private ones, a graph that features all of them—each public and private—might be chosen by utilizing the Overpass QL code to specify a customized filter [18], code 6:

Madrid_graph = ox.graph_from_place('Madrid, Spain', simplify= False, 
    custom_filter=
    '["area"!~"yes"]'
    '["highway"!~"cycleway|motor|proposed|construction|abandoned|platform|raceway"]'
    '["foot"!~"no"]["service"!~"private"]["access"!~"private"]' )

Code 6. Python 3.11.5

4.2.-Procesing the info.

As defined within the introduction, for vector calculation causes, the “unsimplified” OSMnx graph for Madrid has been chosen. Nevertheless, which means the variety of nodes within the NetworkX graph is kind of massive, specifically 465,976, in comparison with 154,311 within the simplified community of Madrid. This, along with the complexity of a metropolis like Madrid, makes the calculation course of described above take fairly a very long time, relying on the {hardware} used. If there are {hardware} limitations, there are fascinating publications price consulting, which might velocity up the calculations of the Python engine, as is the case of utilizing the Numba library [11].

4.3.- The Approximate Nature of the Resolution.

The vary of city conditions associated to business premises is huge. For instance, there are business premises whose façades are usually not steady. In such circumstances, authorized laws require contemplating the a part of the façade that’s most related to every particular case. Even in these conditions, the answer is pretty exact. Nevertheless, it stays an approximate answer that serves as a helpful start line for an in depth on-site evaluation.

4.4.-Simplification.

For the sake of readability, up to now solely the minimal distance limitation between pharmacies of 250 m alongside a pedestrian route has been thought of. As indicated in part 2.- METHOD, it’s also needed for a pharmacy to respect a minimal distance of 150 m from well being centres. Having seen the methodology, this could simply be finished by including the well being centres of Madrid, publicly out there as csv file within the internet of the Group of Madrid [19]. We proceed with the identical methodology as within the case of pharmacies to create the graphs containing factors positioned lower than 150 m from every well being centre; on this case nx.mills.ego_graph([...], radius=150, centre=True, distance=’size‘). Then, within the ‘Grid Overlay’ part, we superimpose this graph with the one for pharmacies within the MultiGraph.nx.compose_all() step. Subsequently subtracting this complete set from the Madrid metropolis graph.

4.5.- Functions aside from these regarding consolidated city land.

Though this publication has handled the case of finding pharmacies on consolidated city land, NetworkX functionalities in Python may also be used to review the perfect places for pharmacies in growing city areas that don’t but have city providers and services put in. This may be finished via centrality measures. There are very fascinating examples of utilizing centrality measures to analyse an city community, for instance within the case of an city biking community [16]. Within the case of pharmacies, the NetworkX “betweenness centrality” measure could be an fascinating candidate to assist decide essentially the most interconnected pedestrian routes in a growing city space, which is a fascinating characteristic to host a pharmacy, as they are usually the place most pedestrians flow into. That is the criterion used to analyse the development factors of cycle lane networks in Copenhagen [20]. However this can be a completely different downside from the one addressed on this publication, and needs to be handled in one other publication.

4.6.- Dialogue of the result.

As indicated within the introduction, the given answer is topological in nature. For instance, in Fig. 5, the sides highlighted inside inexperienced squares “a” correspond to roads in a really large avenue in Madrid, the “Paseo de La Castellana”, with a number of lanes at completely different ranges and boulevards, which pedestrians can solely entry via only a few zebra crossings following a circuitous route. These ‘edges’ have been chosen within the computation exactly for that reason: though their Euclidean distance to the closest pharmacies will not be massive, the precise route a pedestrian has to take to achieve them is for much longer, as they will solely be accessed by way of just a few zebra crossings following a circuitous route. Nevertheless, because of city planning constraints, they don’t seem to be appropriate places for a pharmacy.

As defined above, after figuring out the sides that respect the limitation of distances between pharmacies following this system, it’s essential to additional analyse them when it comes to: availability of business actual property in them to deal with a pharmacy and the chances provided by city planning on permitted makes use of and actions on them. An instance is the highlighted inside inexperienced sq. ‘b’. This can be a massive city plot belonging to the general public water provide firm in Madrid, ‘Canal de Isabel II’, which additionally features as a inexperienced area within the metropolis. On this case, regardless of having been chosen for computation, it isn’t an appropriate area to deal with a pharmacy because of city planning and possession points. Regardless of its Euclidean proximity to the encompassing pharmacies, the computation has chosen these edges due to their tough accessibility, as they’re surrounded by a wall, which requires many detours to enter them following a pedestrian route from the encompassing places.

The chosen examine space has a excessive saturation of pharmacies, primarily because of the truth that a lot of them had been put in earlier than the regulation of distances between pharmacies got here into drive. As well as, because of the city chaos of the realm, pedestrian routes are very circuitous. Because of this, regardless of the excessive density of pharmacies within the city space, the computation has been capable of finding gaps that would a priori home pharmacies. A few of them are inscribed in cyan ellipses and circles, Fig. 5.

Fig. 5. Particular circumstances. Personal elaboration utilizing OSMnx. Knowledge © OpenStreetMap contributors, out there below the Open Database License

5.- Knowledge Availability and Disclaimer

The datasets utilized on this examine are publicly accessible and licensed for any use by the Autonomous Group of Madrid, Spain. Road community information was sourced from OpenStreetMap © OpenStreetMap contributors, by way of the OSMnx Python library, and is out there below the Open Database License (ODbL): https://opendatacommons.org/licenses/odbl/1.0/ . Geospatial layers as pharmacy places, had been derived from publicly accessible GeoJSON and csv recordsdata hosted on https://datos.comunidad.madrid/group/salud and https://datos.comunidad.madrid/catalogo/dataset/6f407280-6ab1-43fb-bb48-ab954ec6edae/useful resource/130c1f6e-b131-44a1-94c9-00c9bb807ca6/obtain/oficinas_farmacia.csv , by the Autonomous Group of Madrid, Spain, explicitly allowing any use, as could be seen within the corresponding Phrases of Use and Licensing Data at https://www.comunidad.madrid/servicios/012-atencion-ciudadano/aviso-legal-privacidad.

The methodological design, technical implementation (e.g., community evaluation by way of NetworkX), and spatial computations offered on this article had been developed independently by the creator. All analytical workflows, visualizations, and conclusions are unique contributions, free from third-party mental property restrictions. For transparency, direct hyperlinks to information sources has been supplied within the References and Knowledge Availability sections of this text.

Notice on Legal responsibility:

In accordance with the publicly out there information sources employed, as defined within the earlier “Knowledge Availability” part, the creator hereby disclaims any duty for penalties, damages, or losses ensuing from the entry, use, or interpretation of the data offered on this work, as finished within the Phrases of Use of such information sources. This text is meant strictly for academic functions and doesn’t represent skilled or business recommendation. Customers are urged to independently validate information and seek the advice of related specialists earlier than making use of any findings.

6.- REFFERENCES

[1]         Jefatura del Estado de España, “Ley 29/2006, de 26 de julio, de garantías y uso racional de los medicamentos y productos sanitarios.,” BOE, vol. 178, no. BOE-A-2006-13554, pp. 28122–28165, 2006.

[2]         Jefatura del Estado de España, “Ley 16/1997, de 25 de abril, de Regulación de Servicios de las Oficinas de Farmacia.,” BOE, vol. 100, no. BOE-A-1997-9022, pp. 13450–13452, 1997.

[3]         Ministerio de Sanidad y Seguridad Social de España, “ORDEN de 21 de noviembre de 1979 por la que se desarrolla el Actual Decreto 909/1978, de 14 de abril, en lo referente al establecimiento, transmisión e integración de Oficinas de Farmacia.,” BOE, vol. 302, no. BOE-A-1979-29679, pp. 28975–28977, 1979.

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[10]      G. Boeing, “A multi-scale evaluation of 27,000 city avenue networks: Each US metropolis, city, urbanized space, and Zillow neighborhood,” Environ. Plan. B City Anal. Metropolis Sci., vol. 47, no. 4, 2020.

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[12]      Y. Chang, “Connecting and interpolating POIs to a street community,” In direction of Knowledge Science, 2019. [Online]. Out there: https://towardsdatascience.com/connecting-pois-to-a-road-network-358a81447944. [Accessed: 07-Oct-2024].

[13]      Comunidad de Madrid, “Datos Abiertos Comunidad de Madrid. Portal de transparencia,” 2024. [Online]. Out there: https://datos.comunidad.madrid/group/salud. [Accessed: 01-Oct-2024].

[14]      Comunidad de Madrid, “Oficinas de Farmacia, csv recordsdata.,” Portal de Datos Abiertos Comunidad de Madrid. Portal de transparencia, 2024. [Online]. Out there: https://datos.comunidad.madrid/catalogo/dataset/6f407280-6ab1-43fb-bb48-ab954ec6edae/useful resource/130c1f6e-b131-44a1-94c9-00c9bb807ca6/obtain/oficinas_farmacia.csv.

[15]      G. Boeing, “OSMnx: New strategies for buying, setting up, analyzing, and visualizing advanced avenue networks,” Comput. Environ. City Syst., vol. 65, pp. 126–139, 2017.

[16]      M. A. Alattar, C. Cottrill, and M. Beecroft, “Modelling cyclists’ route alternative utilizing Strava and OSMnx: A case examine of the Metropolis of Glasgow,” Transp. Res. Interdiscip. Perspect., vol. 9, 2021.

[17]      C. R. Harris et al., “Array programming with NumPy,” Nature, vol. 585, no. 7825. 2020.

[18]      G. Boeing, “Use string formatting to insert infrastructure into question,” github, 2017. [Online]. Out there: https://github.com/gboeing/osmnx/blob/v0.5.3/osmnx/core.py#L482-483. [Accessed: 01-Sep-2024].

[19]      Comunidad de Madrid, “Centros de Salud, csv recordsdata.,” Portal de Datos Abiertos de la Comunidad de Madrid. Portal de transparencia, 2024. [Online]. Out there: https://datos.comunidad.madrid/dataset/centros_servicios_establecimientos_sanitarios.

[20]      A. Vybornova, T. Cunha, A. Gühnemann, and M. Szell, “Automated Detection of Lacking Hyperlinks in Bicycle Networks,” Geogr. Anal., vol. 55, no. 2, 2023.

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